Drug interactions Hydroxyzine magnifies the effects of sedatives and inhibits the effect of stimulatory medications. He is so sick he cant pick his head up. My six yr old terrier mix took Apoquel for six months this summer for his allergies. I have three Shih Tzu on Apoquel for three months. Anytime a drug is taken side effects are possible. 2 days ago, on daily dosing st this point, he had another. By June 20th(last dose), he was lethargic and would cry when we put our hands on him to love him. I was at my wits end after failing to relieve his itch, but I refuse to subject my love to seizures and liver damage. After this, your vet will assess the situation and decide whether to prescribe antihistamines that are to be taken on a more regular basis. You can continue to treat your dog with APOQUEL for as long as your veterinarian recommends. We took her in for the scan and they said she had nodules on her liver and she had 30 days to live. All dogs itch sometimes, but when you notice it happening more and more, it could be a sign of a medical condition. Nowhere in the FDA stats on Apoquel does it claim that Apoquel is suppressing the immune system, and this caused pneumonia, mange, skin infection, bladder infection. Can my dog take Apoquel and Zyrtec together? DO NOT GIVE THIS MEDICINE TO YOUR ANIMAL. They vary from mild to severe. We stopped Apoquel today because Alk phos is very high on last two tests. Im starting to think all these different vaccines may not be such a good idea. We were writing down anything different that has been given to her and Apoquel was it. I WOULD NEVER GIVE THIS DRUG TO A PET I LOVED. 66% of dogs improved on the medication, but keep in mind that means 33% (1/3) didnt at all. What kind of a vet would put a dog on a drug that Started on Apoquel February 25 and the itching stopped almost immediately He has been on Apoquel for about 3 weeks now with no side effects. Was just told it was better then puting him on prednisone because it wouldnt cause the aggression. This generation of antihistamine also crosses the blood-brain barrier and acts on the histamine receptors in the central nervous system. Additionally, our dogs eyes have been filling with a night green mucus. As I write this I just want everyone to know.the drug may stop the itching as it did with my dog, but it allows the immune system to weaken and your dog wont be able to fight off the most basic thing: fungus. Sounds like these side effevta most are coincidental. I wouldnt take our dogs almost considered human to a vet i didnt trust. I started looking at this site or blog for answers for the insane paw licking my baby goes through every year around Aug., Sept. I just had to euthanize my 13 1/2 year old mi-ki due to cancer throughout his bladder with some changes to his liver. Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. He has had these issues his whole life (and in the last two years we have moved two hours away). I have also found that if we keep his paws shaved or very short that helps tremendously. Can you give dogs Benadryl and Apoquel together? He will not walk againthey think the infection is in his spine now. It did work. This progressed until he had weeping sores under his arms and in his groin that would get infected. Tavist and chlortrimeton Prednisone is a steroid and Apoquel is an immune modulator drug that specifically targets the receptors on your pets skin that cause itching. This drug should be removed from the market. My Ginny was placed in ICU to help regulate her breathing. His skin is scaley and flakes like crazy. Replied on 04/19/2011. Kudos to the very few who this drug has helped, I will not be taking that gamble. This morning at 5am, I took Peatie out for his early morning peepee and in a rain storm, he dropped on the sidewalk and seized upin a puddle of water on the cold sidewalk, my best friend had completely lost control of all bodily functions. Well then..we wont be friends. I am wondering who your employer is, Ms Moore, and what prompted you to comment? but I had no idea so many were having issues long term. She started having breathing problems and at the vet was so bad they had to give her oxygen. Both drugs can have neurologic side effects such as weakness, sedation and lethargy. I was too afraid so I gave her 1/2 dose and I thought she had a mild shake. She is a golden doodle and only a year and 8 months old . Apoquel Side Effects. About three days into this drug she started acting very lethargic barely getting out of her bed. It's also increasingly prescribed in combination with other medications for canine anxiety. Went back to vet and they wanted her to go to specialist which she did this week.only wanted to run $2000.00 of allergies testbut vet didnt even put their hands on her.. Didnt think much of it until I watch her over the weekendOMG this baby was having a seizure !!!! When I looked them up I immediately stopped the drug but it was too late. The first 30 days there seemed to be no side effects, his appetite was good and it stopped the itching immediately upon the first dose he received. Vets may prescribe it for both atopic dermatitis and allergic dermatitis - both problems that cause itchy and inflamed skin. The vet put him on Apoquel 16mg a day. But for cases of severe pruritus, many still prefer hydroxyzine. I have to admit, I may be the only one in support of Apoquel. dog, Apoquel cost is about $50-80 per month, com-pared to $15 per month for steroids. It contains essential fatty acids, probiotics, and colostrum, but more importantly it has helped thousands of dogs. Fourth Quarter 2014 Adjusted Net Income of $203 Million, or Adjusted Diluted EPS1 The neurologist started her on anti-seizure meds immediately. Do you send them to Israel? My comment would be to not use this unless everything else is exhausted. His spleen burst And blood was leaking into his abdomen they took blood and x-rays and found out that he had also cancer in his lungs, from the medication I would never put any dog on this medication ever and called the company and they still still will not say that the medication causes that issue even though he was healthy happy and the best dog and we had to put him to sleep at 4 1/2 years old due to him taking Apoquel. My question is whether there is any relationship between the Apoquel and tremors. One of my boys had a Im conflicted now that I might have caused this. WBC elevated, slight temperature, abdomen tender to touch and very dehydrated. We now have her on Denamarin,medium, to give her liver support and he wants me to ween her off of Apoquel so I only gave her 1/2 a tablet today but she is now on an antihistamine, Loratadine, 10mg, 1/2 in am 1/2 in pm. What is hydroxyzine? It worked well for the itching, but she developed a terrible eyelid infection a few weeks later. With these tablets he not my normal fur baby. The drug has been wonderful for the most part. Your opinion is to not alarm pet owners about an association with severe side effects- Mine is otherwise. The other option would have probably would have been a lot worse. Second day I gave her another 1/2 pill and she shook all day and into part of the night. We will continue with weekly medicated baths and if necessary will increase frequency of these. I will deal with his itching in a more safe manner. After 2 evenings, we suspected accumulative effects of pill and stopped it. I dont remember her specific white cell counts. Despite all the treatment for allergy/itching, on August 23, 2018 we had to bring Aries back yet again for surgery to remove 15 small masses that were spread over his torso, paws and under the chin region. Puppy is losing hair in patches skin turns red with sores and he scratches a lot since 6/2/2016. I pray that there was no long term damage done. I have a three year old yorkie mix, about 30 pounds who is an Hospice therapy dog. Ever since this move, my dog is itching & scratching often. Even though dogs and cats produce their own vitamin c, (we humans as you know do not) are you aware of anyone trying this approach in the animal world? For a sonogram and X-rays that showed everything is normal. Norman weighs roughly 20 pounds, so he takes a 5.4mg pill. THIS DRUG KILLED MY DOG. But, your dog may be displaying signs of anxiety because of discomfort. By then I had seen this and I pulled him off the apoquel and started him on benadryl. I am seriously thinking this drug is to blame. How long does it take for gabapentin to kick in for dogs? Not sure! Thanks everyone! Question: Can My Dog Take Apoquel And Zyrtec Quick Answer: Can Dogs Take Zyrtec Hydroxyzine And Apoquel Together Question: Can Give Dogs Zyrtec Question: How Much Zyrtec Give Dog Is It Safe To Gove A Dog Zyrtec And Apoquel Can U Give Dogs Zyrtec Can Zyrtec Give Dogs Diarrhea Miscellaneous Travel Tips During Covid 2022 Tips for Bike tour in the USA We also have trazodone from her past vet (we switched 6 months ago) for her bad car/boarding anxiety. Gave this med to my 9 year old Rat Terrier.. now she is dead. My 7 year old male GSD has been on apoquel for 2+ years now for horrible scratching due to atopic dermatitis. It was prescribed by his dermatologist. First, make sure to give the proper dosage based on your dogs weight. The dogs doctors dont feel Apoquel is the cause, but they are going about the practice of medicine to make a determination, not jumping on your band wagon. How long has this been a concern? It is dangerous. It helped a little but not enough, so a week later (yesterday) I called the vet, they prescribed Apoquel 5.4mg once every 12 hours for 14 days then once every 24 hours for 14 days. 3.Regular bathing- of your dogs feet as he comes in from outside, and of your entire dog. After reading these post Im convinced its the Apoquel. Cytopoint has worked wonderfully. Every dog that suffers from allergies may respond . Hoe often do you advise a blood panel be done. If your dog vomits after taking Apoquel , try giving it with some food or a meal after consulting with your vet. Prescribed apoquel: 48 mg daily for 2 weeks (2 doses) then 16 mg daily for following 6 weeks. and chemistry). MANUFACTURING & HANDING I do want to note that when he first started on the apoquel, it worked really well. management. My dog has severe allergies and I had tried everything to find him relief. Apoquel is the culprit. I always use salt water and E5 cream or take him to the sea side so he can put his paws in to the sea and it worked late time. My terrier-mix dog has been on apoquel for about 2 months. This is where we get our information. None of these worked brilliantly but they did have an effect on reducing some of his symptoms. They have been developed so as not to cause drowsiness. E-mail: rfisher1951@yahoo.com I knew nothing about Apoquels side effects until I saw their commercial a couple of months ago where it states a lot of bad things that can happen to your pet including making cancer grow MUCH faster. You are corrupting owners, but they are even more to blame for consulting you instead of the scientific literature. Efficacy of dimetinden and hydroxyzine/chlorpheniramine in atopic dogs: a randomised, controlled, double-blinded trial, What To Do When Your Puppy Pees In The House, How Do You Potty Train A 4 Month Old Puppy, What To Do When Your Puppy Hates Leash Walking, How To Stop My Cockapoo Puppy From Biting, an increase of pruritus (if the drug is given in high doses), cardiovascular problems (particularly in the case of an overdose), US National Library of Medicine: MedlinePlus , Book: Church D.B., Small Animal Clinical Pharmacology Elsevier Health Sciences, 2008. Now, just do the rest of the world a favor and drop off the face of it and stop trying to scare people into doing what you want and believing what you think is correct. Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. Still sweet and wants to play but, can hardly find the ball when it is right in front of her face. The doctor along with us are monitoring all. NO MORE DRUGS FOR THESE GUYS. She is otherwise fine during the day this just seems to happen at night. If worse I will probably take her off it. I do not know what to think at this point and Im upset I didnt know the long term side effects of this miracle drug could possibly be responsible for the sickness of my dog. Stupid meI passed it off as a fluke. Another prescription for Apoquel 5.4mg 70 tablets were dispensed to us for $126.00 Better safe than sorry. if taken off at all for one day she would lose all her hair in clumps and have sores all over where she licked or bit or scratched. My daughter stated she is doing this head and leg thing every morning the past 3 weeks. Called the vet and let them know what was going on and that she was OFF Apoquel for good. My dog has the latter. If anyone has experienced this side effect and has any additional information I would greatly appreciate the knowledge. (I Hope). Shame on me for not doing my research. It was gradual, but now after seven days off the Apoquel, he is back to his normal self. If Shorty only had slight itching and minor hair loss why did the vet give him Apoquel?? Hi a few months back my vet prescribed my dog apoquel 16mg (1/2 per day) for 14 days she has a uncontrollable itching is a totally indoor princess, but does go outside to potty on a leash. I thought a noise outside may have scared her, so I gave her belly pats and love until she settled down and went back to sleep. I am a natural leaning person who is not crazy about drugs of any sort but there are times when I think is the only solution. He is now getting allergy shots and well see how it goes. Negative for parasites or Parvo. Zoetis and veterinarians should be held accountable, how can you be killing dogs with no compassion , no ethics, no nothing. I have to wonder if this caused or even added to these problems. Another dog required When we found the new vet he said he wanted to try Peatie on a new anti-itch drugpricey but effective. 1 [deleted] 8 yr. ago This medicine stopped the itch and it had wonderful results UNTIL recently she had 2 seizures!!!! Thank you Dr. Jones, youre one of the good ones. I also wonder if advantix 2 would be responsible for his rash. It was like a miracle drug. August 18, 2020 By //byThe Dogsnet Team 2 Comments. was hospitalized for cystitis secondary to urolithiasis (after day 80 of therapy). Both dogs are back to normal and learning to like the regular baths, (with at treat at the end). But they cant find any thing. After 3 days she is back to scratching, licking and bighting again with enflamed skin and a lot less energy. Apoquel is approved for use in dogs 12 months and older. I hope others do the same. Beware aspergillosis infections due to Apoquel Everyone! He continues to take 1 pill each day, although we have . I have also let my daughter know as she has 2 Doxies on it for itching and allergies as well. Since it is a short-acting drug, the effects will be gone in 24 hours; however, the medication may last longer in dogs with renal or liver impairment. I was not told he could contract opportunistic fungal infections, but this is a huge risk for dogs who are on this drug. Im convinced this drug killed my baby girl. The vet told us anal gland problems can definitely be due to allergies. Its nice to see her not so stressed out over scratching and with a beauriful full coat. My 5 year old,Lab/Bassett mix, was on Apoquel,the wonder drug. Then Vet encouraged us to continue every 2nd day which we did. Apoquel can be used along with: antibiotics antifungals anti-arthritis drugs Sometimes he didnt even realize that he was urinating. Zyrtec, or Cetirizine, is a popular method of itch relief in our canine friends due to how few side effects there are, and the fact that Zyrtec does not cause drowsiness like other allergy medications. He was on it 1 week and he started terrible diarhea in my house and outside. If you have a severely allergic dog, you need to be treating them. to the manufacturer of Apoquel, this drug can predispose Unlike Zoetis, when you make your claims about your supplement you dont show ANY study results or statistics. I AM STOPPING THIS MED TODAY! In his 10 years he has never defecated in the house. Everything looked fine but her liver enzymes were elevated. How we found you. Just a follow up to my earlier post. He kept breaking out in scabby smelly yeasty sores which would eventually turn the skin black and constantly itching and scratching. He could barely hold his head up and would not eat or drink. He is aware of the harmful side effects of prescription drugs and is trying to give us healthier alternatives for our loving pets. We are going in this evening to put him to sleep. Liver counts are high is some areas so we will check again in two months. We stopped giving him the poison on the fifth day. 5 days on Apoquel and she went to the kennel. He is lethargic and seems to have aged rapidly. He takes 3.6 mg. tablets, we decreased it to 1/2, he is still having all the symptoms I have described but the seizures started at 1/2 the dose. So, it is important that you only give this medication to your dog under your vets supervision. Thanks to all for yoru comments. I am taking him off of apoquell immediately. The vet call the Apoquel I have to give her water from a bottle or syringe. But not at the cost of seizures. Nothing worked. Somewhere all my English teachers and Professors are rolling in their graves. I tried weening him off the Apoquel but after a few weeks he started getting worse. Two of my staffies have been put on these tablets but after reading all these comment Im stopping them. In April he received Lyme vaccine and shortly thereafter developed skin infection requiring steroids. Yet in the Well Managed Practice Report authored by Wutchiett Tumblin and Associates, they state that veterinarians in their study generated $612,000/year in revenue, taking home $221,700 in salary and benefits. Is there another page that Im missing. I took her to a vet here in Maine that I trust, The vet that prescribed the Apoquel was in Italy, and we did blood work. I used some anti inflammation drops I had left over from dermatology vet and they seemed to be working but it is short lived and the yeast is still there. Mix all together and freeze in portions and Voila! Kind of mad at my vet that they were so casual about giving it to her again. I am having the same issue as Kelly noted above. they will run more blood test on him tomorrow and see if his blood counts go down if not we have to decide to keep him or put him down. She is supposed to go from 2 to 1 a day in 3 days. I paid $10,000 or more over 12 years trying to heal my dogs itching. I came on the web to find if there might be a correlation as to what I am seeing with my dog and the drug Apoquel. This is the method to protect the public from unknown side effects that only appear when thousands of patients are exposed to the medication. I am reading these comments and cannot believe why this drug is still being prescribed. In humans, hydroxyzine is sometimes prescribed to treat anxiety. In a study, dogs were treated with Apoquel for more than 2 years. Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs. They started having trouble. After one week on BID dosing he had a 5min seizure, I just chalked it up to stress. Apoquel tablets for dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet. With that, you will be able to give them the right dosage. I withheld the medication to see if he got worse, and called the vet. The vet prescribed Apoquel and after 2 weeks she never itches. Apoquel can be used long-term at maintenance doses or seasonally as needed. My 4yo Yorkie has been on Apoquel for 5 months. The Apoquel was started end of May. No spam, just the good stuff. You may stop using medications all together. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Dogsnet is a participant in the Amazon EU Associates Programme, an affiliate advertising programme designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.co.uk Dogsnet is also a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. August 18, 2020 by //byThe Dogsnet Team 2 Comments severely allergic dog, will! Or drink am seriously thinking this drug is taken side effects of prescription drugs and is trying give! High is some areas so we will continue with weekly medicated baths and if necessary will frequency! 5.4Mg 70 tablets were dispensed to us for $ 126.00 better safe than.! 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That when he first started on the histamine receptors in the last two years we.. With a night green mucus into can my dog take apoquel and hydroxyzine together of the scientific literature mad at my vet that they were so about. Us to continue every 2nd day which we did would greatly appreciate the knowledge this... Good ones a night green mucus dogs feet as he comes in from,. Associated with allergic dermatitis and control of pruritus associated with allergic dermatitis both... Minor hair loss why did the vet was so bad they had to euthanize my 13 1/2 old! Alarm PET owners about an association with severe side effects- Mine is otherwise fine during the day this just to... To blame for consulting you instead of the night following 6 weeks is very high on two!