If the heart is hit, Isaac will take damage, Most enemies will target the heart over Isaac himself, Blood donation machines and devil beggars can be used for free. The laser hits up to 13 times if an enemy stays inside it for the duration, Has a chance to drop from the Envy and Super Envy miniboss fights, Item Pool: Item Room, Envy Miniboss, Super Envy Miniboss, * item room, treasure room, item room pool, red, lips, white, eyes, UNLOCK: Unlock this item by beating the Basement 40 times and defeating the Steven boss, *, black, white, face, eyes, mouth, golden chest pool, +10% chance of a devil/angel room opening while held, A second Pentagram will give an extra +5% chance, Counts as 1 of 3 evil items needed towards the Leviathan transformation, Item Pool: Boss Room, Curse Room, Devil Room, Demon Beggar, Crane Game, * curse room pool, devil pool, devil room pool, devil deal, boss room pool, boss room item, Carry them with you", "The walls will harden over time. If a pushed enemy hits a rock or wall forcefully enough, they take 10 damage, UNLOCK: Unlock this item by destroying 100 poops, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, Based on the Steam Workshop mod created by Ink Tears, UNLOCK: Unlock this item by having two items or effects that grant homing shots at once (e.g. Can be negated with Black Candle, Bad Gas - Isaac farts, poisoning enemies around him, Bombs are key - Switches number of bombs and keys, Explosive Diarrhea - Spawns five live troll bombs behind Isaac, one per second, Full Health - Restores all your empty red heart containers, Health Down - -1 HP. 3 keys = 25% chance. Stopwatch: The slowdown will make hard bosses much easier. Find it . It isn't 100% effective but the effect is very strong and will deflect most shots under a bullet hell situation. ), I would also add the inverted cards, The Stars? Using active items gives a damage up that scales with the charge time, ??? *, brown, red, tup, carton, box, golden chest pool, gold chest pool, Item Pool: Boss Room, Gold/Stone Chest, Mom's Chest, *, white, necklace, grey, gray, moms pearls, mom pearls, The Car Battery causes your spacebar item to activate twice on each use, For example, with Yum Heart you would heal 2 full red hearts instead of 1, Upon use, gives you a duplicate of each familiar you have for the current room, It will not 'double' your familiars as the tagline suggests - if you have 2 of one kind, it will only give you an extra one, If the familiar only appears when taking damage (i.e. See next icon for Tainted character effects, Isaac - All new pedestal items cycle through two options. If the enemy dies while in this state they will drop 1-4 coins, Rainbow poop Dips charm enemies and have a chance to spawn 1/2 a red heart on death. This room basically serves as a consolation prize if you fail to get keys to drop, but it also makes Ascension runs much easier, because you can skip Item Rooms to get a Planetarium, but pick up the skipped items as you ascend back up to Home. Can only be accessed via the Red Key, Crystal Key or Cracked Key. Repentance also disrupts just about every accepted strategy players have built up over the last several years. Stat Down pills do nothing, and items like Experimental Treatment increase stats but don't reduce any, This effect works on items that apply negative stat modifiers, such as Soy Milk, This effect works for anything that gives temporary buffs, like Devil/Strength cards, or kill bonuses like Bloody Lust, If you somehow lose Rock Bottom, your stats will go back to normal, UNLOCK: Unlock this item by defeating the Boss Rush as Jacob & Esau, Bombs now explode with a random effect (e.g. Enemies that are killed by the ice tears will become frozen, Frozen enemies never unfreeze and are considered dead by the game. Stat Up becomes Stat Down), Any 'Stat down' pills you take give you a permanent +0.6 Damage Up (Horse pills +1.2), Most other pills spawn a black heart when used, including R U A Wizard?, Amnesia, Bad Trip, ?? Beyond the womb floor, replaces all coin and key spawns with a random pickup as follows: Bomb - 26.6% chance. Will take red hearts first before any other, Eve starts with this item after donating 439 coins to the Greed Donation Machine, UNLOCK: Unlock this item by beating Satan with Eve, Item Pool: Item Room, Curse Room, Demon Beggar, * devil pool, devil room pool, devil deal, the lost item pool, starting, silver, grey, gray, Upon use, this item refreshes the current floor with brand new rooms, monsters and items, as if you had entered a new floor, UNLOCK: Unlock this item by beating Satan with Blue Baby, Item Pool: Item Room, Secret Room, Devil Room, Demon Beggar, * secret room pool, item room, treasure room, item room pool, pill, tablet, drug, white, The Binding of Isaac: Repentance is the latest expansion for the iconic roguelike, and to say it brings some seismic changes is an understatement. Throwing this at the Great Gideon boss will trigger a special animation and reveal a crawl space containing several chests and items! The new rooms contain 0-3 Devil Deal Items, 1-3 Black Hearts and random enemies from the Sheol floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Judas, Opens the door to the Blue Womb, regardless of whether you meet the 30 minute speed timer, Opening Pandora's Box while holding this item will ignore the normal effect and instead spawn 6 item pedestals from random item pools. if you have 99 coins it will create 3 x Quarters, 2 Dimes and 4 Pennies. After taking two hits, the fire will be extinguished, The Book can be held at the same time as another active item. You need to move out of the way or it will hurt Isaac, but can be used to open anything requiring a bomb e.g. Based on the Steam Workshop mod created by Strawrat and Aczom, UNLOCK: Unlock this item by dying to your own Ipecac explosion, Upon taking damage, you have a random chance to consume one of your currently held trinkets, gaining its effect permanently, Added as part of the Afterbirth+ Booster Pack #5. (6 full hearts to fully charge), Unless fully charged, hearts picked up are consumed by the Alabaster Box, instead of being added to your life total. achievement (complete a victory lap, defeating the lamb boss), Horf! Damaging the aggressive Blood Puppy will eventually return it to its normal state. This means you can leave rooms before defeating the enemies inside, Doesn't open locked doors, or the door that leads to the Boss Room, Heals one red heart container when picked up, This item causes nearby enemies to be affected by the charm effect, causing them to attack other nearby enemies, The charm effect will wear off very quicky when enemies move away from Isaac, This item causes your tears to become rocks, which have increased knockback and can break other rocks and objects. This can make it confusing while navigating the room, Dataminer will randomly increase or decrease one of your stats by a small amount when used, Gives you the Fruit Cake effect for the room when used, which will give a random tear effect with every tear fired, All visual and tear effects reset after leaving the room, * data miner, red, pickaxe, minecraft, pixel, When used, this item will randomly change you into another character and remove the last item you picked up, All stat changes of the new character are applied (e.g. This is intended give you a guaranteed way to teleport out of the Mom's Foot fight, for accessing the path to the Mausoleum floor. How do you unlock Godhead? Unlockable in this video:Spindown Dice: Defeat Delirium as Tainted Isaac :Rerolls all pedestal items in a room by subtracting their internal ID number by one. * item room, treasure room, item room pool, white, purple, Gives Isaac the ability to fly and spectral tears, * devil pool, devil room pool, devil deal, red, crescent, moon, drop, black, Creates 5 beams of light from the sky that deal damage equal to your tear damage + 20 to any enemies which come into contact with them, The beams have a high chance to spawn on top of enemies where possible, * item room, treasure room, item room pool, feather, white, arrow, Upon death, you respawn in the previous room as Blue Baby with three Soul hearts, This is a one time use item and all new heart containers will be soul hearts, Can be used to unlock some of Blue Baby's secrets before having the character available, * item room, treasure room, item room pool, black, grey, gray, extra life, egypt, grey, gray, Upon taking damage, you have a 20% chance to gain an invulnerability shield for 7 seconds, The chance to gain a shield is affected by your luck stat and at +27 Luck it will activate every time, UNLOCK: Unlock this item by beating the Chest with Maggy, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Based on the Steam Workshop mod created by Amethyst, UNLOCK: Unlock this item by using 5 Gulp! This gives Isaac a bone sword and he goes on a killing rampage, gaining +0.4 Speed, +3 Flat Damage Up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Samson, Activates the Mega Blast item effect, which gives you a giant laser that deals x5 your tear damage per tick to anything in its path and pushing Isaac back by the force, The effect lasts for 8 seconds but does persist between rooms, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Azazel, When used this kills Isaac and revives him with 1/2 a red heart. Counts as 1 of 3 familiar items needed towards the Conjoined transformation. ?, Satan and The Lamb as Tainted Samson, When taking damage you have a chance to explode and deal 185 damage to all enemies around you (Same damage as a Mr. Mega bomb), UNLOCK: Unlock this trinket by defeating Mother as Tainted Samson, Familiars follow Isaac's exact movements, (similar to how Jacob & Esau work) instead of following loosely like they usually do, Holding the drop button (Ctrl on Steam version) causes them to stop moving, Doesn't affect some familiars with specific movement patterns, e.g. Despite my best efforts, it can only load simple mods that consist of scripts, no mods that contain "resources" from my testing (External Item Descriptions does not work, much to my dismay). knife, red, silver, Gives a 33% chance of converting red heart drops into soul hearts. Unlockables can be gained through doing various tasks, such as destroying enough Poop, beating a chapter for the first time, or defeating a boss in a specific way. This includes damage you deal, and environmental damage they take e.g. UNLOCK: Unlock this item by defeating Lil Horn 20 times, When picked up, gives Isaac a random familiar which has a random sprite and tear effect, The familiar will be fully randomized again upon entering the next floor, The appearance is chosen from a random co-op baby sprite, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ashkait and Scayze, A familiar that will transform into another random familiar every 10 seconds, copying their behaviour and effect, Can be any other familiar, including (but not limited to) Lil Brimstone, Bob's Brain, BBF, Meatboy, Rotten Baby, Familiars appear as a white Delirium version of the original, This item gives you 1 bar of charge on your active item for every 15 enemies you kill, Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by Ashkait and Scayze, UNLOCK: Unlock this item by picking up any 3 of these items in a single run: 9 Volt, The Battery, Car Battery, AAA Battery, Watch Battery, When used, the coupon causes one random item in the shop to become free, While held, guarantees a random item or pickup from the shop to be half price, The effect of this item also works in Devil Rooms, allowing you to take one random item for free, Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by Plumbo, *, paper, square, green, pink, white, barcode, letter, postcard, An active that causes all enemy tears to be held in place and then thrown back away from Isaac for a period of 3 seconds, The aura from this item will repel nearby enemies, Added as part of the Afterbirth+ Booster Pack #2, When used, the box will pick up a maximum of 6 items. Item Pool: Item Room, Demon Beggar, Lust Miniboss, * demon beggar pool, demon judgement pool, devil beggar pool, item room, treasure room, item room pool, syringe, needle, injection, the lost item pool, red, Item Pool: Item Room, Boss Room, Demon Beggar, * demon beggar pool, demon judgement pool, devil beggar pool, boss room pool, boss room item, item room, treasure room, item room pool, syringe, needle, injection, green, Has a chance to drop from the Gluttony miniboss fight, * boss room pool, boss room item, item room, treasure room, item room pool, red heart, ballchinnian, ball sack, full heal, gluttony, the lost item pool, * secret room pool, the lost item pool, brown, poop, turd, * secret room pool, silver, grey, gray, skull, Can drop from an exploding slot machine while playing it, * slot machine, arcade machine, money, bill, cash, green, * boss rush pool, boss rush room, item room, treasure room, item room pool, grey, gray, x10, UNLOCK: Unlock this item by beating Mom's Heart 3 times, * secret room pool, the lost item pool, brown, noose, hang, Shows most icons on the map (Shops, Item Rooms, Boss Rooms etc. purple, An orbiting fly which deals 2 contact damage per tick to enemies, * item room, treasure room, item room pool, blue, Has a chance to drop from the Super Gluttony miniboss fight, Item Pool: Item Room, Super Gluttony Miniboss, * item room, treasure room, item room pool, the lost item pool, white, grey, gray, tub, Allows Isaac to fly while the Pony is held, Sets your speed stat to 1.5 if it isn't already that high, When the active attack is used, Isaac will dash across the screen dealing scaling contact damage to anything he hits, Drops from the Headless Horseman boss fight, REPENTANCE - A Pony's charge time has been reduced to 2 (from 4). At +0 Luck theres a ~2.5% chance for this effect to activate, The size of the rift scales with your tear damage, In Antibirth this item was called Oculus Rift, A familiar boil that randomly fires bursts of tears, similar to the Boil enemy. the lost item pool, grey, gray, A familiar which follows Isaac and shoots spectral tears that deal 3.5 damage, Ghost Baby fires tears at a rate of 1 tear per second, Can drop while destroying skulls in the Depths and Necropolis floors, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, white, spoopy, A spacebar item which allows Isaac to fire a blue flame that damages anything in its path for 23 damage per tick, Can cause up to a total of 276 potential damage, The flame destroys enemy shots, making it useful for bullet hell bosses, UNLOCK: Unlock this item by donating 900 coins to the Shop, * shop room pool, shop item pool, blue candle, grey, gray, silver, lamp, lantern, * boss room pool, boss room item, grey, gray, whip, cat o nine tails catonine tails, Upon use, re-rolls all pickup consumables in the current room into another random kind of pickup, This includes all types of pickup such as hearts, bombs, keys, coins, pills, tarot cards, chests, trinkets etc, UNLOCK: Unlock this item by beating the Chest with Isaac, * item room, treasure room, item room pool, dice pip, red, A familiar which follows Isaac and shoots two normal tears at once in a V-shaped pattern, Each of Harlequin Baby's tears deal 4 damage, Harlequin Baby fires tears at a rate of 1 tear per second, * item room, treasure room, item room pool, bug, eyes, pink, red, Tears now become missiles which deal huge damage to anything nearby, This item places a controllable red target on the ground which will cause a missile to fall from the sky and hit it after a short period of time, UNLOCK: Unlock this item by beating Challenge #19 (The Family Man), Item Pool: Secret Room Item Room (very low weight), * item room, treasure room, item room pool, fetus in a jar, bug, white, hat, pink, If a tear kills an enemy, it continues to travel forward with the leftover damage, * item room, treasure room, item room pool, large eye, cyclops, one eye, blue, white, A shadow follows Isaac and stomps on enemies randomly, dealing 40 damage per stomp (2 damage ticks at 20 damage each), * item room, treasure room, item room pool, white, yarn, wool, spider, Upon use, does 10 damage to all enemies in the room and gives them a slowing effect for 4 seconds, REPENTANCE - Enemies killed by Spider Butt will now spawn friendly blue spiders, * item room, treasure room, item room pool, brown, red, web, Gives Isaac an orbital knife that blocks shots and deals 15 damage per tick on contact with enemies, The highest damage orbital in the game, dealing 225 damage per second, Synergises very well with invulnerability items such as Book of Shadows, UNLOCK: Unlock this item by beating the Chest with Eve, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, bloody, The damage done by Glass Cannon is calculated as follows: dmg = (dmg * 10) + 10 (i.e. Has a small chance to take you to the I AM ERROR room, and a smaller chance to teleport to a Black Market, Addicted - Causes you to take a full heart of damage for all sources for the current room. treasure room, item room pool, white, Upon use, consumes a coin and deals damage to everything in the room, Damage dealt is equal to your tear damage * 2 + 10, REPENTANCE - Damage buffed, previously it was damage * 2. For Items it increases by 2 coins * the number of purchases. This is located on Corpse II, which requires a certain sequence of events. * secret room pool, item room, treasure room, item room pool, 25, grey, gray, silver, devil pool, devil room pool, devil deal, Converts most negative pills into their positive counterparts, e.g. Can fire tears but is immune to damage, Tainted Eden - Items taken before Birthright no longer get rerolled when taking damage, Tainted Lost - Grants an extra life. This deals 1 damage per tick, High tear damage will cause this item to become very powerful for rooms with a lot of enemies, since they can die instantly and render the room harmless, Enemies which spawn after the first few seconds of each room are not affected by this item, e.g. Spoon Bender, Telepathy for Dummies, I - The Magician), While held, gives you a small chance to gain a bone heart everytime you take damage, REPENTANCE - Finger Bone's chance to grant a bone heart has been increased to 5% per hit taken (from 2%), UNLOCK: Unlock this trinket by defeating Ultra Greed as The Forgotten, Teleports the player to the first room of the current floor, There is a guaranteed Fool card in the Depths 2, if you bomb the skull with an X on it. hearts, keys, bombs, coins, pills, cards, trinkets, batteries etc, After the first drop, he has a 67% chance to drop a pickup after 3 coins and a 33% chance to drop a pickup after 4 coins, Bum friend also has a chance to spawn items from the Beggar Item Pool, Counts as 1 of 3 bum items needed towards the Super Bum transformation, * item room, treasure room, item room pool, baby, pink, Item Pool: Devil Room, Curse Room, Red Chest, Gold/Stone Chest, * curse room pool, red chest pool, red chest item pool, golden chest pool, gold chest pool, devil pool, devil room pool, devil deal, dead, cat, grey, gray, guppy head, guppys head, Taking an eternal heart to the next floor or collecting two on the same floor gives you an extra heart container, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, No coding knowledge needed! Changed to 2 room recharge, * golden chest pool, gold chest pool, item room, treasure room, item room pool, bob sloth, After like 800h, it got to the point where i rarely lost any run. Pools: Curse Room, Key Master, Mom's Chest (0.5), Red Chest (0.1), Secret Room, Unlock Condition: Open Mom's Chest in Home. white, grey, gray, A familiar that follows isaac around dropping white creep which slows down enemies that walk over it, Spawns 1-2 familiar blue spiders after every room, * item room, treasure room, item room pool, white, ball, dripping, A familiar that is controlled via the arrow keys and will automatically fire a laser if anything is in its line of sight, Robo-Baby 2.0's lasers deal 3.5 damage per hit, UNLOCK: Unlock this item by beating Challenge #16 (Computer Savvy), * robo baby 2.0, item room, treasure room, item room pool, red, eyes, grey, gray, robot, A familiar which follows Isaac and spawns a blue flies as you're firing tears, Rotten Baby can only create one fly at a time, meaning if he has created a fly he cannot make another until it is used, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, dead, baby, Counts as 1 of 3 evil items needed towards the Leviathan transformation. For the current room, tears now have the Spoon Bender effect, which allows them to curve towards enemies and gives them a purle appearance. Counts as 1 of 3 angel items needed towards the Seraphim transformation. A slow pulsing outline HUD effect appears for cards that would be buffed by Tarot Cloth, To see the full list of Tarot Card effects, check out the Mechanics > Tarot Cloth page, Every time you take damage, 10 high damage tears are fired in a circle around you (similar to the Tammy's Head effect), Tear damage is equal to Isaac's tear damage + 25 flat damage, Additionally, has a chance to activate the Anemic effect when taking damage for 2 seconds, Similar to Tammy's Head, this item synergizes with a lot of items (i.e. It stops moving while Isaac is firing tears and upon releasing the fire button, King Baby will teleport back to your location, King Baby will always appear first in the queue of familiars, REPENTANCE - Familiars now automatically aim at enemies when being commanded by King Baby. Tears can still hit Isaac if gravity applies for too long, Allows Isaac to squeeze between some objects, This item has a chance to spawn an additional curse room on each future floor, Causes a penny to spawn in all future Curse Rooms, Tears fired from your left eye gain roughly +28% fire rate increase, Causes your tears to be fired at staggered rates, Allows Angel Rooms to appears even if a Devil deal has been taken before, All shops now contain a trapdoor with a ladder, which leads down to a special shop. You must collect every item in both the base game and in the DLC, this requires you to pick up the item at least once (Note: Challenge mode and Seed mode disables trophy progress for this, items obtained in these modes never count. Item Pool: Angel Room *, Sol. ?, Satan and The Lamb as Tainted Judas, Changes Devil Room layouts. ?, Paralysis, Retro Vision, I'm Excited, While held, gives you an orbital that blocks enemy shots and deals contact damage equal to 3.5 per tick, While the active key is held down, Isaac gains +0.5 Speed and all of your orbitals spin faster and deal more damage, Orbital damage is equal to 1.5 x OrbitalDamage + 6 while this effect is active, On death enemies now fire tears in random directions, which can damage other enemies, The amount of tears created by this effect depends on the total health of the enemy killed. Here is the requirements for getting 1001% completion rate in Binding of Isaac. All I could remember to prioritize was Revelation and Twisted Pair, so this helps. ), Prevents your stats from being reduced any more for the rest of the run, e.g. 13 Holy Mantle. More items consumed = more chance for this effect. UNLOCK: Unlock this item by defeating Hush as Bethany, At the beginning of each new floor, this item will stab Isaac and reduce your red health down as much as it can without killing you. REPENTANCE - Dead Sea Scrolls now displays the name of the given effect, and can no longer give Kamikaze. When used, turns every normal enemy in the room into poop! in shops or devil rooms), The only way to survive the falling sword is either through extra lives, by using items that would make you invincible, such as Gnawed Leaf or playing as The Lost. Spoon Bender will give them a homing effect, and status effects like fear/poison will spread onto all enemies the electricity chains to, Tears which fall naturally to the floor at max range do not generate sparks, It's possible to fire tears at a wall to create electricity that damages enemies on the other side of the wall, *, silver, metal, grey, gray, blue, jacob ladder, jacobs ladder, Each tear now has a small chance to be a spectral blue flame instead, which deals damage to enemies that come in contact with it, The fire will remain in place and shrink in size when deals damage to something. Cube of Meat after defeating a Horseman, REPENTANCE - It is now possible to see items again that have been rerolled away, preventing emptying the item pool and 'Breakfasting', REPENTANCE - Chaos now assigns a "weight" to item pools based on how many items are in the pool. Both the box and trinket are consumed when this happens, UNLOCK: Unlock this trinket by defeating Isaac, ?? 15 Of The Best Items In The Binding Of Isaac 15 Mutant Spider. ItemID: 588 "Radiant victory" Quality: 2. . This mechanic is very useful on Greed and Greedier modes, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Keeper, *, orange, brown, yellow, gold, coin, cent, Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health, UNLOCK: Unlock this item by defeating Delirium on The Void floor with Eve, When used, this item permanently removes one of your red heart containers and gives you a flat +0.2 Damage Up, the Anemic effect (+1.5 Range Up + red creep trail) and a Cube of Meat, The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent, Only works for red hearts and has no effect when used if you only have soul/black hearts, Has no recharge time and can be used as often as you like, It is possible to generate multiple meatboys by stacking more than 4 Cubes of Meat, When used, this item gives you the effect of a random item for the rest of the room, Using this item multiple times in the same room will replace the previous item's effect with a new one, Certain items can be activated with this item which have unexpected effects and many items will do nothing, Items do not grant consumable drops which would normally occur when that item is picked up, Most flight-granting items have cosmetic effects only, and will not allow you to fly, Items that usually give HP up will not give extra health when gained from Metronome, UNLOCK: Unlock this item by defeating Greedier Mode with Eden, This dice allows you to press the Drop key to cycle between all possible dice effects and pick one to use, Charge time scales based on the chosen dice, updating every time you use it, Possible dice include: D1, D4, D6, D8, D10, D12, D20, D100. 3c pickups become 2c, Taking more than 1 steam sale reduces the price of all items even further, This item is called Steamy Sale on PS4, PS Vita, Xbox One and Switch versions, probably due to copyright reasons, Item Pool: Shop, Greed Miniboss, Shopkeeper, * shop room pool, shop item pool, red, pink, white, paper, Spawns 6 troll bombs at random locations around the room, Bombs are effected by other passive bomb items, Has a chance to drop from the Pride miniboss fight, Item Pool: Item Room, Library, Pride Miniboss, * Anarchist's Cookbook, Anarchists Cookbook library pool, library room, book room pool, item room, treasure room, item room pool, +4 damage from Curved Horn instead of 2, -4 Tear Delay from Cancer instead of 2), Item Pool: Shop, Greed Mode Shop, Mom's Chest, Randomly while firing tears, Isaac will stop firing and turn red, where he will charge and release a lot of 'tears' in one go. Increases the time that status effects stay on enemies. ?, Satan and The Lamb as Tainted Bethany, Taking damage gives you a chance to spawn a flame orbital, similar to the ones created by Book of Virtues, Entering an Angel Room gives you +5 flame orbitals. ?, Satan and The Lamb as Tainted Eden, Each brand new room, this trinket has a chance to transform into a copy of a random passive item, which gives you the effect for the duration of this room, UNLOCK: Unlock this trinket by defeating Mother as Tainted Eden, Gives a small chance to spawn a friendly Bony when clearing a room, which will throw bones at enemies until it takes enough damage to die, Can be either the regular white Bony or the black variant, UNLOCK: Unlock this trinket by defeating Isaac, ?? Find it . This effect is stackable, *, the lost item pool, pink, red, guts, intestine, tube, Gives Isaac a higher chance to find hearts from drops after clearing a room and from chests, * , the lost item pool, red, purple, childs heart, child heart, UNLOCK: Unlock this item by beating the Dark Room with Judas, Gives Isaac a higher chance to find keys and chests, Grants a secondary chance of any non-specific heart drop turning into a soul heart, * , the lost item pool, white, grey, gray, circle, round, moms pearl, The fire rate increase is applied in such a way that the higher your tear stat is, the more effective Cancer is, Breaks the normal fire rate cap, allowing you to fire faster than the normal maximum, You have a chance when taking damage to gain +1.8 Damage Up for the rest of the room, Gives Isaac a higher chance to find bombs, Picking up the Match Stick is the only way to remove the Tick trinket, UNLOCK: Unlock this item by blowing up 20 shop keepers (this includes the ones in the secret room), When you take damage while on 1/2 a heart, you are teleported back to the previous room. 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